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Latham Advises AbbVie on Collaboration and Option Agreement With Xilio Therapeutics and Related Equity Investment

February 14, 2025
Firm represents the global pharmaceutical company in the collaboration to develop novel tumor-activated immunotherapies.

AbbVie (NYSE: ABBV) and Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, has announced a collaboration and option-to-license agreement to develop novel tumor-activated, antibody-based immunotherapies, including masked T-cell engagers, leveraging Xilio's proprietary technology.

Under the terms of the agreement, Xilio will receive US$52 million in total upfront payments, including a US$10 million equity investment, and will be eligible to receive up to approximately US$2.1 billion in total contingent payments for option-related fees and milestones plus tiered royalties.

Latham & Watkins LLP advised AbbVie in the transaction. The collaboration and option agreement was led by New York partner Aaron Gardner and San Diego counsel Robert Yeh, with associate Patrick Chew; the equity investment was led by New York partner Nathan Ajiashvili and counsel Lindsey Mills.

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